Preparation of MSDS｜LIFE SCIENCE LABORATORIES,LTD.

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All the studies for preparation of MSDS (Material Safety Data Sheet) are conducted in accordance with the
OECD Guideline to respond to GHS (the Globally Harmonized System of Classification and Labelling of Chemicals).

Type of study
Animals/bacterial strains/cells
Duration of the study

Acute toxicity studies.

Limit test (2000/5000 mg/kg) (TG420)

Male or female mice or rats

Approx.
1 month
Dose finding studies (TG420, TG423, TG425)

Male or female mice or rats

Approx.
1.5 months

Skin corrosion/irritation studies (TG404)

3 male rabbits

Approx.
1 month

Serious eye damage/eye irritation studies (TG405)

3 male rabbits

Approx.
1 month

Skin sensitization studies (TG406)

20 female guinea pigs

Approx.
2 months

Mutagenicity studies

Ames test (bacterial reverse mutation test) (TG471)

5 bacterial strains

Approx.
1 month
Chromosomal aberration test (TG473)

Cultured Chinese hamster cells

Approx.
3 months

Fish toxicity studies (TG203)

Japanese rice fish (7/group)

Approx.
1 month

Please feel free to consult us regarding details and costs of the studies (free quotation).