• Type of study
• Animals/bacterial strains/cells

• Number of participants
• Duration of the study

Single oral dose toxicity(at a single dose level of 2000 mg/kg)

• ≥ 5 rats or mice/sex

  Approx. 1 month

Primary skin irritation

• 3 male rabbits

  Approx. 1 month

Cumulative skin irritation(14-day continuous application)

• 3 female guinea pigs

  Approx. 1.5 months

Phototoxicity(Morikawa’s method)

• 5 guinea pigs

  Approx. 1 month

Skin sensitization(Maximization/Adjuvant and Patch/Buehler Tests)

• 20 female guinea pigs
  (25 female guinea pigs for the Buehler Test)

  Approx. 2 months

Photosensitization(Adjuvant and Strip Test)

• 20 female guinea pigs

  Approx. 2 months

Eye irritation

• 3 male rabbits

  Approx. 1 month

Genotoxicty

• Ames test (bacterial reverse mutation test)

  5 bacterial strains
   

  Approx. 1 month
   

• Chromosomal aberration test

  Cultured Chinese hamster cells

  Approx. 3 months

Human patch test(24-hour closed patch test)

• 40 participants

  Approx. 1 month

Our services also include tests in Japanese participants for labeling of “Stinging tested”.
Please feel free to consult us regarding the details and costs of the studies and so forth (free quotation).